====== Gelbes Fett ======

Assoziiertes Gen: BCO2 (//β-carotene 9′,10′-oxygenase//)

Chromosom: OCU1

Vererbung: monogen; rezessiv (del)

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**Tabelle:** Bekannte Varianten des BCO2
^Symbol^Variante/ Mutation(en)|^Funktion/ Mechanismus^Phänotyp^Rassen^
^ ^DNA^Protein^::: ^::: ^::: ^ 
|ins |Wildtyp | | |Weißes Fettgewebe bei ins/ins oder ins/del((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)) | | 
|del |AAT //In-frame//-Deletion, Codon 248, Exon 6((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)) |Fehlen der Aminosäure Asparagin|Gestörter Carotinoid-Stoffwechsel |Anreicherung von [[naehrstoffe:fett|Carotinoiden aus der Nahrung]], insbesondere Xanthophyllen, im Fettgewebe/ gelbes Fettgewebe bei del/del((Willimott, S. G. 1928. On the pigment of the fat of certain rabbits. Biochemical Journal, 22(4), 1057.))((Castle, W. E. 1933. The linkage relations of yellow fat in rabbits. Proceedings of the National Academy of Sciences, 19(11), 947-950.))((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)) |//Flemish Giants// und Kreuzungen((Castle, W. E. 1929. The rex rabbit. Journal of Heredity, 20(5), 193-199.)); Kreuzungen((Castle, W. E. 1933. The linkage relations of yellow fat in rabbits. Proceedings of the National Academy of Sciences, 19(11), 947-950.)); Kreuzungen von //Flemish Giant//, //New Zealand Red// und //Termond White// (Polen)((Strychalski, J., Gugołek, A., Brym, P., Antoszkiewicz, Z., & Chwastowska-Siwiecka, I. 2019. Polymorphism of the BCO2 gene and the content of carotenoids, retinol, and α-tocopherol in the liver and fat of rabbits. Revista Brasileira de Zootecnia, 48, e20180243.)) |

Weiterführend:\\ Strychalski //et al//., 2022((Strychalski, J., Gugołek, A., Antoszkiewicz, Z., Fopp-Bayat, D., Kaczorek-Łukowska, E., Snarska, A., ... & Matusevičius, P. 2022. The effect of the BCO2 genotype on the expression of genes related to carotenoid, retinol, and α-tocopherol metabolism in rabbits fed a diet with aztec marigold flower extract. International Journal of Molecular Sciences, 23(18), 10552.))\\ 
Strychalski //et al//., 2023((Strychalski, J., Gugołek, A., Kaczorek-Łukowska, E., Antoszkiewicz, Z., & Matusevičius, P. 2023. The BCO2 Genotype and the Expression of BCO1, BCO2, LRAT, and TTPA Genes in the Adipose Tissue and Brain of Rabbits Fed a Diet with Marigold Flower Extract. International Journal of Molecular Sciences, 24(3), 2304.))

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