Unterschiede

Hier werden die Unterschiede zwischen zwei Versionen angezeigt.

--- genetik:haarfarbe_tyrp1 [2026/10/05 20:02] – [Geschichte] kathrin
+++ genetik:haarfarbe_tyrp1 [2026/10/30 23:05] (aktuell) – [Haarfarbe - TYRP1 (Brown)] kathrin
@@ Zeile 16: / Zeile 16: @@
 ^deutsch (englisch) ^DNA^Protein^::: ^::: ^::: ^
 |C (//B//) |Wildtyp |Enzym bestehend aus 537 Aminosäuren((Utzeri, V. J., Ribani, A., & Fontanesi, L. 2014. A premature stop codon in the TYRP 1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). Animal Genetics, 45(4), 600-603.)) |Oxidation von DHICA bei der [[physiologie:fellhaarfarbe#Melanin-Synthese in den Melanosomen|Eumelanin-Synthese]] |"Schwarz" | |
-|c (//b//) |Nonsense-Mutation g.41360196G>A (OryCun2.0)((Utzeri, V. J., Ribani, A., & Fontanesi, L. 2014. A premature stop codon in the TYRP 1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). Animal Genetics, 45(4), 600-603.)) |p.W190ter; vermutlich verkürztes TYRP1-Protein, dem die Tyrosinase-Domäne fast vollständig fehlt((Utzeri, V. J., Ribani, A., & Fontanesi, L. 2014. A premature stop codon in the TYRP 1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). Animal Genetics, 45(4), 600-603.))|Keine Synthese von schwarzem Pigment |"Braun" |Havanna (ANCI, Italien)((Utzeri, V. J., Ribani, A., & Fontanesi, L. 2014. A premature stop codon in the TYRP 1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). Animal Genetics, 45(4), 600-603.)) |
+|c (//b//) |Nonsense-Mutation g.41360196G>A (OryCun2.0)((Utzeri, V. J., Ribani, A., & Fontanesi, L. 2014. A premature stop codon in the TYRP 1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). Animal Genetics, 45(4), 600-603.))((Utzeri, V. J. (2017). Analysis of animal genetic resources for the identification of polymorphisms associated with phenotypic features and evolutionary aspects. [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Scienze e tecnologie agrarie, ambientali e alimentari, 29 Ciclo.)) |p.W190ter; vermutlich verkürztes TYRP1-Protein, dem die Tyrosinase-Domäne fast vollständig fehlt((Utzeri, V. J., Ribani, A., & Fontanesi, L. 2014. A premature stop codon in the TYRP 1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). Animal Genetics, 45(4), 600-603.))((Utzeri, V. J. (2017). Analysis of animal genetic resources for the identification of polymorphisms associated with phenotypic features and evolutionary aspects. [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Scienze e tecnologie agrarie, ambientali e alimentari, 29 Ciclo.))|Keine Synthese von schwarzem Pigment |"Braun" |Havanna (ANCI, Italien)((Utzeri, V. J., Ribani, A., & Fontanesi, L. 2014. A premature stop codon in the TYRP 1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus). Animal Genetics, 45(4), 600-603.))((Utzeri, V. J. (2017). Analysis of animal genetic resources for the identification of polymorphisms associated with phenotypic features and evolutionary aspects. [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Scienze e tecnologie agrarie, ambientali e alimentari, 29 Ciclo.)) |
 ===== Geschichte =====